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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM15
All Species:
10.91
Human Site:
T758
Identified Species:
30
UniProt:
Q13444
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13444
NP_003806.3
814
87717
T758
R
A
L
L
A
R
G
T
K
S
Q
G
P
A
K
Chimpanzee
Pan troglodytes
XP_513846
831
89236
T775
R
A
L
L
A
Q
G
T
K
S
Q
G
P
A
K
Rhesus Macaque
Macaca mulatta
XP_001112574
775
83647
P724
R
S
P
K
S
Q
G
P
A
K
P
P
P
P
R
Dog
Lupus familis
XP_865076
843
90172
A762
R
V
L
L
M
P
G
A
K
A
E
L
A
D
R
Cat
Felis silvestris
Mouse
Mus musculus
O88839
864
92645
T759
R
A
Q
Q
M
T
G
T
K
Q
A
S
V
V
S
Rat
Rattus norvegicus
Q9QYV0
816
88034
T760
R
A
Q
Q
M
P
G
T
K
P
Q
G
P
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001136322
922
101009
S773
P
A
R
S
S
R
S
S
K
L
N
H
V
R
T
Frog
Xenopus laevis
O42596
935
104143
K802
N
S
A
S
S
S
K
K
R
S
A
I
L
S
H
Zebra Danio
Brachydanio rerio
XP_001335318
961
104960
Y739
S
R
G
I
T
V
S
Y
I
E
Y
C
M
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
86.4
79
N.A.
75.8
81.6
N.A.
N.A.
36.6
28.2
34.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.4
87.5
85.6
N.A.
82.7
87.9
N.A.
N.A.
51.9
43.3
47.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
20
33.3
N.A.
33.3
60
N.A.
N.A.
20
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
53.3
N.A.
33.3
60
N.A.
N.A.
33.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
56
12
0
23
0
0
12
12
12
23
0
12
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
0
67
0
0
0
0
34
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% H
% Ile:
0
0
0
12
0
0
0
0
12
0
0
12
0
0
0
% I
% Lys:
0
0
0
12
0
0
12
12
67
12
0
0
0
12
34
% K
% Leu:
0
0
34
34
0
0
0
0
0
12
0
12
12
0
0
% L
% Met:
0
0
0
0
34
0
0
0
0
0
0
0
12
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
12
0
12
0
0
23
0
12
0
12
12
12
45
12
0
% P
% Gln:
0
0
23
23
0
23
0
0
0
12
34
0
0
0
0
% Q
% Arg:
67
12
12
0
0
23
0
0
12
0
0
0
0
12
23
% R
% Ser:
12
23
0
23
34
12
23
12
0
34
0
12
0
12
12
% S
% Thr:
0
0
0
0
12
12
0
45
0
0
0
0
0
12
12
% T
% Val:
0
12
0
0
0
12
0
0
0
0
0
0
23
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _